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Selective alteration of the microbiota for immune regulation

机译:选择性改变微生物群以进行免疫调节

摘要

The present invention relates to a method of modulating immune cells in a patient by altering the patient's microbiota. The invention also relates to methods of modulating treatment or treatment in a subject by altering the microbiota of the subject. The invention also relates to cell populations, systems, arrays, cells, RNA, kits and other means for providing same. In one example, advantageous selective targeting of particular species in human intestinal microflora using inducible nucleic acid modification is performed to effect the alteration.
机译:本发明涉及通过改变患者的微生物群来调节患者的免疫细胞的方法。本发明还涉及通过改变受试者的微生物群来调节受试者的治疗或治疗的方法。本发明还涉及细胞群体,系统,阵列,细胞,RNA,试剂盒和用于提供其的其他手段。在一实例中,使用可诱导的核酸修饰对人肠道菌群中的特定物种进行有利的选择性靶向以实现改变。

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