Use of microbiome profiles to detect liver disease

摘要

Methods are provided for detecting liver fibrosis or for differential diagnosis of non-alcoholic fatty liver disease (NAFLD) in a subject. The method analyzes the biological sample from the subject to determine the intestinal microbiome signature for the subject, and the intestinal microbiome signature is scrutinized relative to the reference intestinal microbiome signature to detect the presence of liver fibrosis. Or detecting the absence.