Monoclonal antibodies, compositions and methods for detecting mucin-like protein (MLP) as biomarkers for ovarian cancer and pancreatic cancer

摘要

In various embodiments, the invention provides an anti-mucin-like protein (MLP) monoclonal antibody for detecting MLP as a biomarker for mucin-secreting cancers, eg, ovarian cancer or pancreatic cancer, Compositions and methods are provided. So far, early detection of ovarian malignancies is an unmet need. Currently used tumor-related biomarkers include, for example, CA-125, which is a relatively non-specific tumor marker, but none of these are capable of early detection of ovarian malignancies. The present invention addresses this issue.