Small molecule inhibitors of nuclear translocation of androgen receptor for the treatment of castration resistant prostate cancer

摘要

Compounds according to formula (III) or Table A or stereoisomers thereof, pharmaceutically acceptable salts or esters, pharmaceutical compositions comprising said compounds and at least one pharmaceutically acceptable additive, and a therapeutically effective amount A method of treating prostate cancer in a subject comprising administering to said subject a compound of Also, a method of treating prostate cancer in a subject comprising administering to the subject a therapeutically effective amount of an agent, said agent being a compound of Formula I or Formula II or a pharmaceutically acceptable salt or ester thereof. Methods are disclosed herein.