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A composition for preventing or treating menopause, comprising Lactobacillus acidophilus

机译:预防或治疗更年期的组合物,其包含嗜酸乳杆菌

摘要

The present invention relates to a novel Lactobacillus acidophilus YT1 (Accession No .: KCCM11808P) strain, and a composition for preventing, improving, or treating menopause as an active ingredient comprising Lactobacillus acidophilus comprising the novel strain About. The present inventors established a menopausal animal model through ovariectomy, confirmed changes in the distribution of intestinal microorganisms from this, and identified and isolated a novel Lactobacillus acidophilus strain among lactic acid bacteria whose distribution was significantly reduced in the menopause model In addition, the new strains and the previously reported Lactobacillus acidophilus strains confirmed the effects of improving menopausal symptoms such as suppression of body fat increase, suppression of bone density decrease, suppression of increased pain sensitivity, and relief of depression. did. The composition comprising the Lactobacillus acidophilus according to the present invention is expected to be usefully used for the prevention, improvement, or treatment of menopause. [Selection] Figure 11c
机译:本发明涉及新型嗜酸乳杆菌YT1(保藏号:KCCM11808P)菌株,以及用于预防,改善或治疗更年期的组合物,所述组合物包含所述新型菌株约氏菌作为包含嗜酸乳杆菌的活性成分。本发明人通过卵巢切除术建立了更年期动物模型,从中证实了肠道微生物分布的变化,并在更年期模型中分布明显减少的乳酸菌中鉴定并分离了一种新型嗜酸乳杆菌菌株。先前报道的嗜酸乳杆菌菌株证实了改善更年期症状的作用,例如抑制体内脂肪增加,抑制骨密度降低,抑制疼痛敏感性增加和减轻抑郁。做到了。预期根据本发明的包含嗜酸乳杆菌的组合物可有效地用于预防,改善或治疗更年期。 [选择]图11c

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