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Solar screening functional substance screening method and solar screening efficacy evaluation method

机译:日晒功能物质的筛选方法及日晒效果的评价方法

摘要

Unlike a conventional method for evaluating a degree of ultraviolet protection through visual evaluation, the disclosed method for measuring a sunlight protection function can accurately and objectively measure and determine a degree of sunlight protection by measuring a change due to a material to be measured with respect to an expression amount of skin tissue antimicrobial peptides (AMPs) in skin cells, which decrease from exposure to sunlight, and/or a generation amount of S-nitrosylated protein. Additionally, the disclosed measurement method can determine whether blue/violet light of wavelengths of 400-500 nm, which induces the most skin damage among visible rays, is blocked and provide a more specified sunlight protection effect evaluation result. Moreover, by using the disclosed measurement method, a degree of sunlight protection can be indexed, and a sunlight protection composition for protecting normal skin from the blue/violet light can be provided.
机译:与通过视觉评估来评估紫外线防护程度的常规方法不同,所公开的用于测量防晒功能的方法可以通过测量由于相对于待测材料的变化而准确,客观地测量和确定防晒程度。皮肤细胞中皮肤组织抗菌肽(AMPs)的表达量(由于暴露于阳光下而减少)和/或S-亚硝基化蛋白的生成量。另外,所公开的测量方法可以确定在可见光中引起最大的皮肤损伤的波长为400-500nm的蓝/紫光是否被阻挡并且提供更具体的日光防护效果评估结果。此外,通过使用所公开的测量方法,可以指示防晒的程度,并且可以提供用于保护正常皮肤免受蓝/紫光的防晒组合物。

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