[PROBLEMS] To efficiently predict the effects and side effects of a test substance in humans. A group of data indicating the behavior of biomarkers in a plurality of different organs collected for each non-human animal from a non-human animal individually administered with a plurality of existing substances whose actions in humans are known, and the existing The human action of the test substance is determined from the behavior of biomarkers in multiple organs of a non-human animal to which the test substance is administered, including training of artificial intelligence using known actions in humans for each substance as training data. Provide artificial intelligence trained in the training method of artificial intelligence model to predict. [Selection] Figure 1
展开▼