Enhanced pluripotent cells and microvascular tissues and methods of use thereof

摘要

The present disclosure provides compositions having enhanced biological activity and methods of use in the treatment of pain associated with disease or tissue damage and disease states. Embodiments of the invention include isolated pluripotent cells, processed microvascular tissues, cell membranes obtained or derived from the cells or tissues, wherein the cells, tissues or membranes are angiogenic or It has anti-inflammatory activity. Embodiments of the invention include compositions exposed to treatments that typically reduce the efficacy of cells or proteins but surprisingly improve the biological activity of cells or tissues.