Regulation of G protein coupled receptors (GPCRs) by imipripidone

摘要

Imipridon selectively modulates class AG protein coupled receptors (GPCRs), such as the dopamine receptor D2-like subfamily, and pathologies and disorders that require such regulation, such as cancer, mental disorders and bacterial infections It was found to be useful for the treatment of In addition, methods are provided to determine if a subject having the above conditions is likely to respond to a treatment regimen such as imipridone administration. In addition, methods are also provided for evaluating the efficacy of a treatment regimen, such as imipridone administration, monitoring a subject having the above condition, or predicting the prognosis of a subject having the above condition. 【Selection chart】 None