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Bispecific cell-activating antigen binding molecule that binds mesothelin and CD3

机译:结合间皮素和CD3的双特异性细胞激活抗原结合分子

摘要

The present invention relates generally to novel bispecific antigen binding molecules for T reactivation and redirection to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, vectors and host cells containing such polynucleotides. The present invention further relates to methods of generating the bispecific antigen binding molecules of the present invention and methods of using such bispecific antigen binding molecules for the treatment of disease. [Selection figure] None
机译:本发明总体上涉及用于T重新活化和重定向至特异性靶细胞的新型双特异性抗原结合分子。另外,本发明涉及编码这种双特异性抗原结合分子的多核苷酸,含有这种多核苷酸的载体和宿主细胞。本发明进一步涉及产生本发明的双特异性抗原结合分子的方法,以及使用这种双特异性抗原结合分子治疗疾病的方法。 [选择图]无

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