首页> 外国专利> Isoindoline-1-one derivatives as cholinergic muscarinic M1 receptor positive allosteric modulator activity for the treatment of Alzheimer's disease

Isoindoline-1-one derivatives as cholinergic muscarinic M1 receptor positive allosteric modulator activity for the treatment of Alzheimer's disease

机译:异吲哚啉-1-酮衍生物作为胆碱能毒蕈碱M1受体阳性的变构调节剂活性,可治疗阿尔茨海默氏病

摘要

The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the prophylaxis or treatment of Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies, and the like. The present invention relates to a compound represented by the formula (I) or a salt thereof. wherein each symbol is as described in the specification, or a salt thereof.
机译:本发明提供了具有胆碱能毒蕈碱型M1受体正变构调节剂活性的化合物,并且用作预防或治疗阿尔茨海默氏病,精神分裂症,疼痛,睡眠障碍,帕金森氏病痴呆症,路易体痴呆等的化合物。本发明涉及式(I)表示的化合物或其盐。其中每个符号如说明书中所述,或其盐。

著录项

  • 公开/公告号JP6517239B2

    专利类型

  • 公开/公告日2019-05-22

    原文格式PDF

  • 申请/专利权人 武田薬品工業株式会社;

    申请/专利号JP20160564111

  • 申请日2015-04-22

  • 分类号C07D209/46;C07D405/04;C07D405/14;C07D401/14;C07D403/10;C07D401/06;C07D401/10;C07D405/06;A61P43;A61P25/28;A61P25/24;A61P25/18;A61P25/20;A61P29;A61P25/16;A61K31/4439;A61K31/4155;A61K31/4035;A61K31/4192;A61K31/501;

  • 国家 JP

  • 入库时间 2022-08-21 12:20:28

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