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Hydrophobic modified peptides and their use for liver specific targeting

机译:疏水修饰肽及其在肝脏特异性靶向中的应用

摘要

The present invention relates to hydrophobic modified peptides for the specific delivery of compounds to the liver, preferably to hepatocytes, in vitro as well as in vivo. The present invention relates to pharmaceutical compositions comprising said hydrophobic modified peptide(s) and the compound(s) to be specifically delivered to the liver. The present invention furthermore relates to the use of the inventive hydrophobic modified peptides as well as to a method for the prevention and/or treatment of liver diseases or disorders.
机译:本发明涉及疏水修饰的肽,用于在体外以及体内将化合物特异性地递送至肝脏,优选地递送至肝细胞。本发明涉及药物组合物,其包含所述疏水性修饰的肽和要特异性递送至肝脏的化合物。此外,本发明涉及本发明的疏水性修饰的肽的用途以及用于预防和/或治疗肝脏疾病或病症的方法。

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