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Three component salts of fumaric acid monomethyl ester and piperazine or ethylenediamine for the treatment of multiple sclerosis

机译:富马酸单甲酯和哌嗪或乙二胺的三组分盐用于治疗多发性硬化症

摘要

The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of salts of formula I or formula II; and methods for treating or preventing multiple sclerosis may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of neurodegenerative diseases and psoriasis.
机译:本发明涉及式I和式II化合物或其药学上可接受的多晶型物,溶剂化物,对映异构体,立体异构体和水合物。该药物组合物包含有效量的式I或式II的盐;可以配制用于口服,颊,直肠,局部,透皮,透粘膜,静脉内,肠胃外给药,糖浆或注射剂的用于治疗或预防多发性硬化的方法和方法。这样的组合物可以用于治疗神经退行性疾病和牛皮癣。

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