首页> 外国专利> Method for estimating Gleason score of prostate cancer, method for estimating pathological staging, and method for obtaining auxiliary information based on content of specific PSA in specimen

Method for estimating Gleason score of prostate cancer, method for estimating pathological staging, and method for obtaining auxiliary information based on content of specific PSA in specimen

机译:基于标本中特定PSA含量的前列腺癌格里森评分的估算方法,病理分期的估算方法和获取辅助信息的方法

摘要

The present invention provides a method for obtaining various types of auxiliary information for diagnosis or treatment of prostate cancer, which can be performed with low invasiveness and low cost. By measuring the content of PSA (Prostate Specific Antigen) having a β-N-acetylgalactosamine residue at the non-reducing end of the sugar chain in the sample, and comparing the measured value with a threshold value, (1) A method for estimating that the Gleason score (primary pattern and secondary pattern) is greater than or less than a predetermined value, (2) a method for estimating that the pathological stage classification (pT) is greater than or less than a predetermined value, And (3) This is a method for obtaining judgment information that diagnosis or treatment should be actively performed because GS at the time of total excision is expected to be higher than GS at the time of biopsy.
机译:本发明提供一种用于获得用于诊断或治疗前列腺癌的各种类型的辅助信息的方法,其可以以低侵入性和低成本来执行。通过测量样品中糖链非还原端具有β-N-乙酰半乳糖胺残基的PSA(前列腺特异性抗原)的含量,并将测量值与阈值进行比较,(1)估算方法格里森评分(主要模式和次要模式)大于或小于预定值,(2)一种估计病理分期(pT)大于或小于预定值的方法,以及(3)这是一种用于获取判断信息的方法,该信息应积极进行诊断或治疗,因为预计完全切除时的GS会高于活检时的GS。

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