5 'nucleotidase, ecto modulator and use thereof

摘要

Described herein are 5'-nucleotidases, compounds that modulate the conversion of AMP to adenosine by ecto, and compositions comprising the compounds, and methods of synthesizing the compounds. Also provided is the use of such compounds and compositions for the treatment and / or prevention of a variety of diseases, disorders and conditions including 5'-nucleotidase, ecto-mediated cancer and immune related disorders. .