Inhibitors selected from JAK inhibitors, ASK1 inhibitors, BRD inhibitors and / or MMP9 inhibitors and BTK inhibitors GS-4059 for treating cancer, allergic disorders, autoimmune diseases or inflammatory diseases Combination

摘要

Provided herein are methods related to therapeutic strategies for the treatment of cancer and allergic disorders, autoimmune disorders and inflammatory disorders, including hematological malignancies. In particular, the method includes administration of a BTK inhibitor and one or more inhibitors. For example, the one or more inhibitors can be JAK inhibitors, ASK1 inhibitors, BRD4 inhibitors or MMP9 inhibitors. BTK inhibitors and methods, compositions (including pharmaceutical compositions, formulations or unit dosages) comprising one or more inhibitors selected from JAK inhibitors, ASK inhibitors, BRD inhibitors and MMP9 inhibitors Products and kits are provided. [Selection] Figure 1