Nucleic acid that suppresses MEX3B gene expression, MEX3B gene expression inhibitor, method for suppressing MEX3B gene expression, and preventive or therapeutic agent for diseases caused by MEX3B gene expression

摘要

Nucleic acid that has low cytotoxicity as a side effect and can suppress MEX3B gene expression, MEX3B gene expression inhibitor containing the nucleic acid, method for suppressing MEX3B gene expression, and preventive or therapeutic agent for diseases caused by MEX3B gene expression To provide. An antisense oligonucleotide having a sequence complementary to an oligonucleotide comprising at least 10 consecutive nucleotides in an untranslated region in an exon of the MEX3B gene, or a double-stranded RNA comprising at least 20 consecutive nucleotides in the untranslated region Alternatively, a nucleic acid that suppresses the expression of the MEX3B gene, which is a DNA encoding the double-stranded RNA.