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Novel synthetic oligomers of Neisseria meningitidis serotype X and methods for their preparation
Novel synthetic oligomers of Neisseria meningitidis serotype X and methods for their preparation
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机译:X型脑膜炎奈瑟氏球菌的新型合成低聚物及其制备方法
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摘要
The present invention relates to synthesis of novel higher oligomers and process of preparing the same. In particular the present invention relates to the chemical synthesis of oligomers of Neisseria meningitidis serogroup X (‘hereinafter Men-X), more particularly tetramer. The present invention provides Men-X capsular oligomers obtained from synthetic pathway using purified saccharides of specific chain length and provides said novel oligomers as candidates for the development of conjugate vaccine against bacterial meningitis caused due to Men-X infections.
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