which activates Wnt/β-catenin signaling and thus treats or prevents diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising Parkinson's disease, strokes, ischemic cerebral disease, epilepsy, Alzheimer's disease, depression, bipolar disorder, schizophrenia; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases."/>
公开/公告号US10314832B2
专利类型
公开/公告日2019-06-11
原文格式PDF
申请/专利权人 SAMUMED LLC;
申请/专利号US201715855463
申请日2017-12-27
分类号A61K9;A61K31/12;A61K31/357;A61K31/381;C07D213/50;C07D319/16;C07D319/18;C07D405/06;C07D405/10;C07D407/10;C07D409/06;C07D409/10;A61K31/4402;A61K31/4433;A61K31/4436;C07C49/784;
国家 US
入库时间 2022-08-21 12:17:01