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Retargeted herpesvirus with a glycoprotein H fusion
Retargeted herpesvirus with a glycoprotein H fusion
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机译:具有糖蛋白H融合的靶向疱疹病毒
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摘要
The present invention relates to the field of disease therapy. More specifically, it relates to a retargeted herpesvirus having a heterologous polypeptide fused to glycoprotein H, wherein the polypeptide targets diseased cells. It also relates to a nucleic acid comprising the genome of the herpesvirus of the invention, a vector comprising this nucleic acid and a cell comprising the nucleic acid or the vector. It further relates to killing cells using the herpesvirus of the invention and to methods for growing it in vitro.
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