首页> 外国专利> Carbon nanotube bioFET with a local amplifier in a system array for analysis of biomarkers and method of analysis of same

Carbon nanotube bioFET with a local amplifier in a system array for analysis of biomarkers and method of analysis of same

机译:在系统阵列中具有用于生物标记物分析的局部放大器的碳纳米管bioFET及其分析方法

摘要

A bioFET cell for measuring a time dependent characteristic of an analyte bearing fluid includes a source, a drain, a semiconductive single wall carbon nanotube network layer extending between the source and drain electrodes and electrically coupled there between, a gate insulatively spaced from and disposed over and extending between the source and drain electrodes, a layer of at least one selected antibody disposed on and linked to the polymer layer to functionalize the semiconductive single wall carbon nanotube network layer to a selected target biomarker corresponding to the at least one selected antibody so that electron transport into the semiconductive single wall carbon nanotube network layer is facilitated, where the source, drain and gate electrodes with the carbon nanotube network layer form a defined channel through which the analyte bearing fluid may flow, and a high impedance source follower amplifier coupled to the source electrode.
机译:用于测量载有分析物的流体的随时间变化的特性的bioFET单元包括源极,漏极,在源极和漏极之间延伸并电耦合在其之间的半导电单壁碳纳米管网络层,与该栅极绝缘隔开并设置在其上方的栅极在源电极和漏电极之间延伸,在聚合物层上设置并连接至少一层所选抗体,以将半导电单壁碳纳米管网络层功能化为对应于至少一种所选抗体的所选靶生物标记,从而电子促进进入半导电单壁碳纳米管网络层的传输,其中带有碳纳米管网络层的源电极,漏电极和栅电极形成了一个确定的通道,载有分析物的流体可以流过该通道,并且一个高阻抗源跟随器放大器耦合到源电极。

著录项

  • 公开/公告号US10324059B2

    专利类型

  • 公开/公告日2019-06-18

    原文格式PDF

  • 申请/专利权人 SENSOR KINESIS CORPORATION;

    申请/专利号US201715724930

  • 发明设计人 JOSH SHACHAR;

    申请日2017-10-04

  • 分类号G01N27/403;G01N33;G01N33/48;G01N27/414;G01N33/543;H01L51;G01N15/06;H01L51/05;

  • 国家 US

  • 入库时间 2022-08-21 12:16:27

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