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Methods for detecting colorectal cancer using a DNA marker of exfoliated epithelia and a fecal blood marker

机译:使用脱落的上皮DNA标记和粪便血液标记物检测大肠癌的方法

摘要

The present invention provides methods and materials related to the detection of colorectal neoplasm-specific markers in or associated with a subject's stool sample. In particular, the present invention provides methods and materials for identifying mammals having a colorectal neoplasm by detecting the presence of exfoliated epithelial markers (e.g., human DNA, tumor assoicated gene alterations, tumor associated proteins) and blood markers (e.g., homoglobin, serum proteins) in a stool sample obtained from the mammal.
机译:本发明提供了与检测受试者粪便样品中或与之相关的结直肠肿瘤特异性标志物有关的方法和材料。特别地,本发明提供了通过检测脱落的上皮标志物(例如人DNA,肿瘤相关基因改变,肿瘤相关蛋白)和血液标志物(例如高血红蛋白,血清蛋白)的存在来鉴定具有大肠肿瘤的哺乳动物的方法和材料。 )取自哺乳动物的粪便样品中。

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