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Functional assay for cancer recurrence and malignant potential
Functional assay for cancer recurrence and malignant potential
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机译:癌症复发和恶性潜能的功能测定
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摘要
Embodiments herein provides an in vitro co-culture system comprising a population of cancer responder cells and a population of non-tumor cells wherein the cancer responder cells can convert to a malignant state and exhibit hallmark malignant phenotype when the cells are placed in a tumor supportive environment. The system is useful for prognosis evaluation of cancer recurrence, malignancy development, cancer drug screening and surveillance for resistance to cancer drug therapy.
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