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Method for treating heart failure with preserved ejection fraction by administering human relaxin-2
Method for treating heart failure with preserved ejection fraction by administering human relaxin-2
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机译:通过施用人松弛素-2以保留射血分数治疗心力衰竭的方法
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摘要
A pharmaceutical composition for treatment of persons afflicted of heart failure with preserved ejection fraction (HFPEF), diastolic heart failure (DHF) or diastolic dysfunction (DF), the composition comprising a therapeutically effective amount of a compound capable of specific binding to the relaxin receptor (RXFP1) present on fibroblasts, fibromyoblasts, endothelial cells, endocardial cells, and cardiomyocytes in the cardiac muscle to increase the heart's stroke volume at lower end-diastolic pressure.
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