首页>
外国专利>
Method of stimulating TLR9-activated immune response
Method of stimulating TLR9-activated immune response
展开▼
机译:刺激TLR9激活的免疫反应的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method of stimulating a TLR9-activated immune response or enhancing a TLR9-activated immune response to an antigen is disclosed herein. TLR9 is the cellular receptor for CpG-ODN, and current developed CpG-ODN has low activity to rabbit TLR9. Here, the method of stimulating TLR9-activated immune response by administering an effective amount of immunogenic composition comprising an antigen and a CpG-ODN comprising GACGTT or AACGTT motif was demonstrated to have potent immunostimulatory activity to rabbit TLR9, and capable of boosting a less toxic and potent antibody response in rabbits.
展开▼