首页>
外国专利>
Antibody-based therapy of transthyretin (TTR) amyloidosis and human-derived antibodies therefor
Antibody-based therapy of transthyretin (TTR) amyloidosis and human-derived antibodies therefor
展开▼
机译:转甲状腺素蛋白(TTR)淀粉样变性的基于抗体的治疗及其人类衍生抗体
展开▼
页面导航
摘要
著录项
相似文献
摘要
Provided are novel human-derived antibodies specific for transthyretin (TTR), preferably capable of binding misfolded, misassembled, and/or aggregated TTR species, as well as methods related thereto. In addition, methods of diagnosing and/or monitoring diseases and treatments thereof which are associated with TTR amyloidosis are provided. Assays and kits related to antibodies specific for TTR or TTR deposits and aggregates are also disclosed. The novel anti-TTR antibodies can be used in pharmaceutical and diagnostic compositions for TTR targeted immunotherapy and diagnostics.
展开▼