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Monoclonal antibody for the diagnosis, treatment and/or prevention of brain tumors and brain lesions

机译:用于诊断,治疗和/或预防脑肿瘤和脑病变的单克隆抗体

摘要

The invention relates to the use of the monoclonal antibody NILO1 for the diagnosis, treatment and/or prevention of brain tumors and lesions. Particularly, the invention relates to methods for the diagnosis of brain tumors and brain lesions in which cells marked with said antibody, or with immunologically active fragments thereof, are detected. The invention also relates to the use of said monoclonal antibody, or immunologically active fragments thereof, as a medicament for the treatment and/or prevention of brain tumors and brain lesions. In a preferred embodiment of the invention, the monoclonal antibody NILO1, or its immunologically active fragments, are humanized.
机译:本发明涉及单克隆抗体NILO1在诊断,治疗和/或预防脑肿瘤和病变中的用途。特别地,本发明涉及诊断脑肿瘤和脑损伤的方法,其中检测标记有所述抗体或其免疫活性片段的细胞。本发明还涉及所述单克隆抗体或其免疫活性片段作为用于治疗和/或预防脑肿瘤和脑损伤的药物的用途。在本发明的一个优选实施方案中,单克隆抗体NILO1或其免疫活性片段被人源化。

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