;or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which act as protein degradation inducing moieties for tripartite motif-containing 24 (TRIM24). The present application also relates to methods for the targeted degradation of TRIM24 through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to TRIM24 which can be utilized in the treatment of disorders modulated by TRIM24."/>
公开/公告号US2019209535A1
专利类型
公开/公告日2019-07-11
原文格式PDF
申请/专利号US201716312591
申请日2017-06-23
分类号A61K31/4365;A61K31/4184;A61K47/55;A61P35;
国家 US
入库时间 2022-08-21 12:13:16