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Use of scintillator-based nanoparticles for in vivo control of light-sensitive bioactive molecules
Use of scintillator-based nanoparticles for in vivo control of light-sensitive bioactive molecules
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机译:基于闪烁体的纳米粒子在体内控制光敏生物活性分子的用途
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摘要
The method for remote, non-invasive in vivo control of the activation of light-sensitive bioactive molecules for the purpose of research or therapy is based on delivering to the required site of the body of nanoparticles along with said light-sensitive bioactive molecules. Nanoparticles' core is made from scintillator material that absorbs X-ray and in response emits visible light; they have biocompatible protective coating and surface targeting agents enabling accumulation at the required site(s) within the body. Irradiation of the site with the highly penetrable X-rays causes nanoparticles to emit visible light which will activate light-sensitive bioactive molecule(s) within this site inducing sought therapeutic effect.
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