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Methods and Apparatus for Creating Particle Derivatives of HDL with Reduced Lipid Content
Methods and Apparatus for Creating Particle Derivatives of HDL with Reduced Lipid Content
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机译:脂质含量降低的高密度脂蛋白颗粒衍生物的制备方法和装置
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摘要
The present invention is directed to systems, apparatus and methods for creating derivatives of at least one form of HDL without substantially affecting LDL. These derivatives of HDL are particles with reduced lipid content, particularly reduced cholesterol content. These particles have the capacity to bind cholesterol and are administered to a patient to enhance cellular cholesterol efflux and reduce cholesterol levels in cells, tissues, organs, and blood vessels. The present method is useful for treating atherogenic vascular disease and may be combined with other therapies such as statins, inhibitors of cholesterol absorption, niacin, anti-inflammatories, exercise and dietary restriction.
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