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N-METHYL-D-ASPARTATE RECEPTOR ALLOSTERIC MODULATORS AND METHODS FOR THEIR USE

机译:N-甲基-D-天冬氨酸受体变位调节剂及其使用方法

摘要

This invention relates to therapeutic compounds and compositions, and methods for their use in the prevention or treatment of neurological disorders. In particular, the invention relates to N-methyl-D-aspartate receptor (NMDAR) allosteric modulators and methods for their use in the prevention or treatment of disorders or conditions caused by or related to NMDAR dysfunctions. The invention also relates to a method for identifying NMDAR allosteric modulators.
机译:本发明涉及治疗化合物和组合物,以及其在预防或治疗神经系统疾病中的用途的方法。特别地,本发明涉及N-甲基-D-天冬氨酸受体(NMDAR)变构调节剂及其在预防或治疗由NMDAR功能障碍引起或与之相关的疾病或病症中的用途。本发明还涉及鉴定NMDAR变构调节剂的方法。

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