Bi-benzyl isoquinoline derivative, preparation method and use thereof in hepatopathy treatment and prevention

摘要

The invention disclosed a compound of general formula (I), a single stereoisomer thereof, a mixture of stereoisomers thereof, and a prodrug, pharmaceutically acceptable salt and metabolite thereof, X₁, X₂, X₃, X₄, R₁, R₂, x, y and z being as defined in the present invention.;