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Substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
Substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
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机译:替代突变受体及其在基于核受体的诱导型基因表达系统中的应用
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摘要
This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to novel substitution mutant receptors and their use in a Group H nuclear receptor-based inducible gene expression system and methods of modulating the expression of a gene in a host cell for applications such as gene therapy, large scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic organisms.
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