Disclosed is multi-device communication system and method based on EPC tunneling. A method of operating a communication control system according to the present disclosure includes: assigning, by a P-GW, an IP address to a first device and a second device being a communication connection target of the first device through LTE initial connection; checking, by first device and the second device, the assigned IP address of each communication connection target device by using a server; determining, by the P-GW, whether or not a destination of a packet received from at least one of the first device and the second device is an EPC internal network; and making, by the P-GW, to an S-GW a request for resetting a tunneling ID of a bearer related to at least one of the first device and the second device according to a result of the determination.
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