Derivatives of 2-aminopyridine as adenosine A_2B receptor antagonists and ligands of the melatonin MT₃ receptors

摘要

The present invention relates to novel pyridine derivatives of formula (I):; as A_2B adenosine receptor antagonists and ligands of MT₃ melatonin receptor, to processes for their preparation, to pharmaceutical compositions comprising said compounds and to the use of said for manufacturing a medicament for the treatment of pathological conditions or diseases that can improve by antagonizing the adenosine A_2B receptor and by inhibition of MT₃ melatonin receptor, such as respiratory disease, metabolic disorders, neurological disorders and cancer.