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HIGHLY LOADED METAL OXIDE MATERIALS BY SELF-ASSEMBLY FOR EXTENDED BIOLOGICALLY ACTIVE MOLECULE RELEASE IN MEDICAL AND DENTAL APPLICATIONS
HIGHLY LOADED METAL OXIDE MATERIALS BY SELF-ASSEMBLY FOR EXTENDED BIOLOGICALLY ACTIVE MOLECULE RELEASE IN MEDICAL AND DENTAL APPLICATIONS
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机译:自组装的高负载金属氧化物材料在医学和牙科应用中扩展的生物活性分子释放
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摘要
A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time.
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