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Method for producing 2,4-dienal acetal compound and 2,4-dienal compound

机译:生产2,4-二醛缩醛化合物和2,4-二醛化合物的方法

摘要

Methods of producing a 2,4-dienal acetal compound and a 2,4-dienal compound useful as synthesis intermediates of a sex pheromone compound having a conjugated diene structure or a conjugated triene structure. More specifically, a method produces a 2,4-dienal acetal compound of Formula (2): R1CH═CH—CH═CH—CH(OR2)(OR3), including a step of subjecting a 2-enal acetal compound having a leaving group X at position C5 and being expressed by Formula (1): R1CHX—CH2—CH═CH—CH(OR2)(OR3) to an elimination reaction in the presence of a base to obtain the 2,4-dienal acetal compound (2); and a method for producing a 2,4-dienal compound of Formula (3): R1CH═CH—CH═CH—CHO, further including a step of deprotecting the 2,4-dienal acetal compound (2) to obtain the 2,4-dienal compound (3).
机译:制备2,4-二烯醛缩醛化合物和2,4-二烯丙基化合物的方法,该化合物可用作具有共轭二烯结构或共轭三烯结构的性信息素化合物的合成中间体。更具体地,一种方法产生式(2)的2,4-二烯丙基缩醛化合物:R 1 CH = CH-CH = CH-CH(OR 2 )( OR 3 ),包括使在位置C5处具有离去基团X且由式(1)表示的2缩醛缩醛化合物的步骤:R 1 CHX- CH 2 -CH═CH-CH(OR 2 )(OR 3 )在碱存在下进行消除反应,得到2,4-二乙缩醛化合物(2);以及制备式(3):R 1 CH = CH-CH = CH-CHO的2,4-二烯基化合物的方法,还包括将2,4-二烯醇缩醛脱保护的步骤化合物(2)得到2,4-二烯基化合物(3)。

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