Method for capturing target substance, solid-phase carrier for capturing target substance, and method for producing solid-phase carrier

摘要

To provide a solid-phase carrier that has extremely low nonspecific adsorption of biological substances such as proteins, peptides, nucleic acids and cells, and is capable of maintaining the activity of bound ligands at a high level; and a method for capturing a target substance using the solid-phase carrier.;A method for capturing a target substance, including: a step for preparing a solid-phase carrier for capturing a target substance, the carrier having a base material, at least a portion of the surface thereof being formed of or coated with a saccharide, and having a linker of 5-100 atoms having a reactive functional group for binding a ligand that specifically binds to the target substance, wherein the saccharide is chemically bound to the linker; a step for binding the ligand to the solid-phase carrier to obtain a solid-phase carrier having a ligand bound thereto; and a step for bringing the solid-phase carrier having the ligand bound thereto into contact with a sample containing the target substance that specifically binds to the ligand.