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Colon cancer gene expression signatures and methods of use

机译:结肠癌基因表达特征和使用方法

摘要

A gene expression signature of colon cancer, microarrays including them and methods of using the colon gene expression signature are provided. The gene expression signature is especially useful for determining the prognosis of a patient diagnosed with colon cancer, such as stage II colon cancer. The gene signature described herein is also useful for determining effectiveness of surgical resection with or without adjuvant chemotherapy, and determining possibility of cancer recurrence in patients with colon cancer.
机译:提供了结肠癌的基因表达标记,包括它们的微阵列以及使用结肠基因表达标记的方法。基因表达签名对于确定诊断为结肠癌(例如II期结肠癌)的患者的预后特别有用。本文所述的基因标记还可用于确定在有或没有辅助化学疗法的情况下手术切除的有效性,以及确定结肠癌患者中癌症复发的可能性。

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