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TRANSDERMAL DRUG DELIVERY DEVICE FOR DELIVERING OPIOIDS

机译:用于递送阿片类药物的透皮药物递送装置

摘要

Systems and methods are provided herein for transdermal delivery of an opioid. The opioids can be delivered in a decreasing dose (dose-tapering) manner to minimize withdrawal symptoms and abuse. The systems are also designed to limit a person besides the patient from receiving the drug with the transdermal delivery device. The systems can also include abuse-deterrence features that limit the ability of a patient or unauthorized user from tampering with the device to receive the active ingredient. Novel transdermal drug delivery formulations are also provided that include an opioid agonist or partial agonist and opioid antagonist which prevent the abuse of formulation.
机译:本文提供了用于阿片样物质的透皮递送的系统和方法。阿片类药物可以减少剂量(逐渐减少剂量)的方式输送,以最大程度地减少戒断症状和滥用。该系统还被设计成限制除患者之外的人使用透皮递送装置来接收药物。该系统还可以包括滥用威慑功能,这些功能限制了患者或未经授权的用户篡改设备接收活性成分的能力。还提供了新颖的透皮药物递送制剂,其包括防止制剂滥用的阿片样物质激动剂或部分激动剂和阿片样物质拮抗剂。

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