Method and Apparatus for Full-System, Cardiovascular Simulation and Prediction

摘要

A system and method for real-time, a closed-loop, complete body hemodynamic simulation of a patient undergoing a surgical procedure is disclosed. A simplified model of blood circulation that is nevertheless comprehensive and derives input representative of the patient's entire circulatory system, is mathematically modeled by a combination of 1-D mathematical models, and lumped parameter models. The system allows a clinician to select an intended intervention that is then computationally simulated in real, or quasi-real, time. The results of the simulation are presented as a heartbeat by heartbeat simulation of clinician selected, relevant hemodynamic parameters, allowing the clinician to decide whether or not to proceed with the intervention. The system includes accurate simulation of the effects of gravity, respiration and natural compensatory mechanisms, including the baroreflex.