首页> 外国专利> DIMERIZATION STRATEGIES AND COMPOUNDS FOR MOLECULAR IMAGING AND/OR RADIOIMMUNOTHERAPY

DIMERIZATION STRATEGIES AND COMPOUNDS FOR MOLECULAR IMAGING AND/OR RADIOIMMUNOTHERAPY

机译:分子成像和/或放射免疫疗法的数字化策略和化合物

摘要

The present invention provides a multivalent compound for targeted molecular imaging and/or targeted drug delivery, wherein two components or targeting molecules each interacts with one or more biomarkers on a cell. The present invention further provides a multifunctional chelator to combine the targeting molecules. The present invention also provides an in vitro high-throughput screening assay to determine the length of the spacer molecules. The present invention also relates to compounds/probes, kits and methods for use in targeted molecular imaging and/or targeted drug delivery.
机译:本发明提供了用于靶向分子成像和/或靶向药物递送的多价化合物,其中两种组分或靶向分子各自与细胞上的一个或多个生物标记相互作用。本发明进一步提供了一种多功能螯合剂,以结合靶向分子。本发明还提供了体外高通量筛选测定法,以确定间隔物分子的长度。本发明还涉及用于靶向分子成像和/或靶向药物递送的化合物/探针,试剂盒和方法。

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