首页> 外国专利> Composition comprising up-converting phosphors for detecting an analyte

Composition comprising up-converting phosphors for detecting an analyte

机译:用于检测分析物的包含上转换荧光粉的组合物

摘要

The present invention relates to a detector matrix for detecting at least one analyte in a sample, preferably a sample of a body fluid, comprising at least one enzyme active in the presence of said at least one analyte and at least one indicator reagent changing at least one optical property dependent on the activity of said enzyme, wherein said detector matrix further comprises up-converting phosphor particles, preferably UV-emitting up-converting phosphor particles. The invention further relates to a test element and a test device for detecting at least one analyte in a sample comprising the detector matrix of the invention, as well as to a method for the manufacture of a detector matrix, a method for the manufacture of a test element, and to a method for detecting an analyte in a sample, comprising contacting a detector matrix according to the invention with a sample suspected to comprise said analyte.
机译:本发明涉及一种用于检测样品,优选是体液样品中的至少一种分析物的检测器基质,其包含在所述至少一种分析物的存在下具有活性的至少一种酶和至少改变至少一种指示剂的试剂。一种光学性质取决于所述酶的活性,其中所述检测器基质还包含上转换荧光粉颗粒,优选发射紫外线的上转换荧光粉颗粒。本发明还涉及一种用于检测包括本发明的检测器基质的样品中的至少一种分析物的测试元件和测试装置,以及一种用于制造检测器基质的方法,一种用于制造检测器基质的方法。测试元件,以及用于检测样品中分析物的方法,包括使根据本发明的检测器矩阵与怀疑包含所述分析物的样品接触。

著录项

  • 公开/公告号US10168321B2

    专利类型

  • 公开/公告日2019-01-01

    原文格式PDF

  • 申请/专利权人 ROCHE DIABETES CARE INC.;

    申请/专利号US201615163153

  • 发明设计人 CARINA HORN;TIMO-JAAKKO VALTA;

    申请日2016-05-24

  • 分类号G01N33/52;G01N21/77;C12Q1/32;C12Q1/26;C12Q1/54;

  • 国家 US

  • 入库时间 2022-08-21 12:05:10

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