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Composition for inducing direct transdifferentiation of somatic cell into vascular progenitor cell, and use thereof
Composition for inducing direct transdifferentiation of somatic cell into vascular progenitor cell, and use thereof
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机译:用于诱导体细胞直接转分化为血管祖细胞的组合物及其用途
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摘要
The present invention relates to a composition for inducing direct transdifferentiation of a somatic cell into a vascular progenitor cell and a use thereof and, more specifically, to a composition for inducing direct transdifferentiation of a somatic cell into a vascular progenitor cell, a pharmaceutical composition for the prevention or treatment of ischemic vascular diseases, a cell therapeutic agent for the prevention or treatment of ischemic vascular diseases, a composition for screening a therapeutic drug for ischemic vascular diseases, a 3D printing biological material composition for the production of an artificial tissue for the treatment of ischemic vascular diseases, and a method for direct transdifferentiation of a somatic cell into a vascular progenitor cell. By producing a vascular progenitor cell by direct transdifferentiation of a somatic cell according to the present invention, it is possible to reduce the production period of the vascular progenitor cell and to avoid the formation of teratoma, which is a side effect of an induced pluripotent stem cell, thereby minimizing the side effects of a stem cell therapeutic agent.
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