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Anti schizophrenic antibody or a fragment of KNN, understand its composition and treatment of inflammation

机译:抗精神分裂症抗体或KNN片段,了解其组成和炎症治疗

摘要

1. Claim 1: an anti schizophrenic antibody or a fragment combined with Kuwait Petroleum Company, characterized in that the antibody or fragment contains (a) a cdr-h1 containing the amino acid sequence SEQ ID 28; (b) a cdr-h2 containing the amino acid sequence SEQ ID 29; (c) a CDR-H3 containing the amino acid sequence SEQ ID 29, including: 29. Amino acid sequence of SEQ ID 30; (d) cdr-l1, including amino acid sequence of SEQ ID 31; (E) cdr-l2, including amino acid sequence of SEQ ID 32;(f) a cdr-l3, comprising SEQ ID amino acid sequence No. 33. 113. Claim 14: a pharmaceutical ingredient characterized by the presence of antibodies in any 1-13 claims or antibody fragments combined with CDU. Requirement 17: typical nucleic acidsBecause it will antibody or link to the RCD part from any 1-13 requirement. 19. Claim 20: a vector 17-19 having the property of containing the nucleic acid in any claim. Claim 23: claim unit 22The characteristic is that the host cell is composed of a first vector and a second vector, Among them, the first carrier includes a nucleic acid that can encode a heavy chain, while the second carrier includes a nucleic acid that can encode a lighter antibody chain, or a fragment in any 1-13 claims that combines with the antibody of CDU. Claim 32: a method for the treatment of inflammation, characterized by the effective supply of antibodies to patients in need of such treatment or part of 1-13 antibodies combined with CDU,This is about inflammation.
机译:1.权利要求1的抗精神分裂症抗体或与科威特石油公司组合的片段,其特征在于所述抗体或片段包含(a)含有氨基酸序列SEQ ID 28的cdr-h1; (b)含有氨基酸序列SEQ ID 29的cdr-h2; (c)CDR-H3,其包含氨基酸序列SEQ ID 29,包括:29.氨基酸序列SEQ ID 30; (d)cdr-1,包括SEQ ID 31的氨基酸序列; (E)cdr-12,包括SEQ ID 32的氨基酸序列;(f)cdr-13,包括SEQ ID的氨基酸序列No.33。113.权利要求14:一种药物成分,其特征在于在任何1-13项或与CDU结合的抗体片段。要求17:典型的核酸因为它会抗体或链接到任何1-13要求的RCD部分。 19.权利要求20:载体17-19,其具有包含任何权利要求中的核酸的性质。 23.权利要求22:特征在于宿主细胞由第一载体和第二载体组成,其中,第一载体包括可以编码重链的核酸,而第二载体包括可以编码重链的核酸。编码较轻的抗体链,或与CDU抗体结合的权利要求1-13中任一项的片段。 32.一种用于治疗炎症的方法,其特征在于向需要这种治疗的患者有效地提供抗体或与CDU组合的1-13抗体的一部分,这与炎症有关。

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