detection and modulation of slit and roundabount (robo) mediated lymphatic vessel formation and their uses

摘要

detection and modulation of slit and roundabount (robo) mediated lymphatic vessel formation and their uses. The invention provides a method for the prevention or treatment of a slit protein-mediated disorder which comprises administering to a subject a therapeutically effective amount of an agent for modulating interactions between the prevention or slit protein and a protein. robot, in which the disorder involves the formation of lymphatic vessels. The invention describes a composition for preventing or treating a slit protein-mediated disorder and a method for predicting or diagnosing a slit protein-mediated disease or disorder.