Process for obtaining acid, 3,5 - diprenyl - 4 - hidroxicinâmico (artepelin (c) of green propolis extract using supercritical carbon dioxide and a co solvent.

摘要

Process for obtaining acid 3.5 - diprenyl - 4 - hidroxicinâmico (artepelin (c) of green propolis extract using supercritical carbon dioxide and the co solvent, the goal of the present invention patent is to reveal in detailAnd demand protection for process conditions and obtaining of green propolis extract.Produced by bees in the apex of the shrubs of species of plant rosemary (baccharis dracunculifolia), using the technology of supercritical extraction.Using carbon dioxide (CO2) and supercritical fluid extraction in the presence of co solvent, preferably ethyl alcohol under conditions of pressure, temperature,The flow of CO2 and other parameters, previously established, where the said extract can subsequently be used for commercial application in formulations of supplements, functional foods,Herbal medicines, pesticides, nutraceuticals, cosmetics, among others, and contains in its composition, the acid, 3,5 - diprenyl - 4 - hidroxicinâmico (artepelin (c) in addition to other active compounds.Such as phenolic compounds and flavonoids. The conditions for the reason of mass of CO2 on the mass of the sample s / F preferential 110.The obtaining of the extracts with high quantities of artepelin c acid (3,5 - diprenyl - 4 - hidroxicinâmico) can be obtained at temperatures of 40 to 50 ° C,The pressures of 250 to 350 to 400bar and presence of 1 to 2% ethanol acting as co solvent.