DUAL AFFINITY REDIRECTION REAGENT, NUCLEIC ACID MOLECULE, PHARMACEUTICAL COMPOSITION AND USES OF THE REDUCTION REAGENT OF DOUBLE AFFINITY

摘要

A reagent re -routing of double affinity, nucleic acid molecule, pharmaceutical composition and uses of the double affinity re -routing reagent refers to antibodies and their fragments that are immunoreative to mammals, and more particularity And, the human B7 -h3 receptor and its use, particularly in the treatment of cancer and inflammation. The invention thus particularly concerns reactive humanized antibodies B7 -h3 and their immunoreative fragments that are able to mediate,And more preferably increase the activation of the immune system against cancer cells that are associated with a variety of human cancers. 1 /1