首页> 外国专利> COMPLEX A VANÁDIO (IV) COMPLEX WITH HYPOGLYCEMANTIC ACTIVITY AND REDUCTION OF TESTICULAR ATROPHY

COMPLEX A VANÁDIO (IV) COMPLEX WITH HYPOGLYCEMANTIC ACTIVITY AND REDUCTION OF TESTICULAR ATROPHY

机译:具有降血糖药活性和减少萎缩性萎缩的钒(IV)复合物

摘要

Complex the base of vanadium (iv) with hypoglycaemic activity and reduction of testicular atrophy. Is this invention a compound of CO -ordination of oxovanydian and binding n,n? -bis -hydroxyethylene nodiamine, presenting this compound with high hypoglycaemic activity and reduction of side effects associated with the male reproductive system, constituting? If so, a promising drug to be applied in diabetes mellitus therapy. This invention presents itself as technological innovation from the point of view: (a) structural, (b) potential hypoglycaemic and (c) reduction of side effects associated with the male reproductive system,Otherwise known as an antithesic effect. This invention presented a reduction in glucose level in diabetic (male) Wistar rats induced by streptozotocin, with an average of below -dose glucose levels already available in the pharmacological market, and avoided the emergence of commonly encont side effects Found in diabetic subjects such as body weight loss, decreased epididymis size, prostate, testicle and seminal gland.
机译:将钒(iv)的基础与降血糖活性和睾丸萎缩降低复合。本发明的化合物是由氧代戊烯酸的CO配位并结合n,n的化合物吗? -双-羟乙烯诺二胺,具有较高的降血糖活性,并减少了与男性生殖系统有关的副作用,构成?如果是这样,那么有希望的药物将用于糖尿病治疗。从以下观点来看,本发明以技术创新的形式呈现:(a)结构性的,(b)潜在的降血糖性的,和(c)与男性生殖系统有关的副作用的减少,否则被称为消感作用。本发明提出了由链脲佐菌素诱导的糖尿病(雄性)Wistar大鼠中葡萄糖水平的降低,在药理学市场上已经有平均低于剂量的葡萄糖水平,并且避免了在糖尿病受试者中发现的常见的不良反应的出现。体重减轻,附睾大小减少,前列腺,睾丸和精腺。

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