herbal biologically active substance with polypharmacological effect

摘要

The invention relates to pharmacology and may be used to produce medicinal agents for treating and preventing viral diseases caused by herpes, influenza and hepatitis b and c viruses, as well as virus-induced immunodeficiencies. A biologically active substance having a polypharmacological effect is made from the green and spiky parts of cereals of the family gramineae, genus calamagrostis adans and / or genus deschampsia beauv, and contains flavonoids, specifically tricine, apigenin, luteoline, quercetin and ramnazine flavonoids aglycones. , and excipients, and has the following composition by weight percentage: flavonoid tricine aglycone and / or flavonoid tricine glycosides: 0.016 to 2.062%; flavonoid aglycone apigenin and / or flavonoid glycosides apigenin: 0.010 to 1.393% / flavonoid aglycone luteolin and / or flavonoid glycosides luteoline: 0.01 to 4.979%; flavonoid quercetin aglycone and / or quercetin flavonoid glycosides: 0.001 to 0.771%; flavonoid aglycone ramnazine and / or flavonoid glycosides ramnazine: 0.104 to 0.203%; excipients: 99,868 to 90,592%. Thus, the biologically active substance is enhanced by determining the specific compositions of its active ingredients, and the physical, chemical and biological characteristics thereof, resulting in the invention of an ideal composition (Figure 1) to achieve an antiviral effect against viruses. specific dosages when creating medicinal forms. In addition, it has been determined that the biologically active substance is an inducer of an endogenous ³-type interferon, has an apoptosis modulating effect, has antioxidant properties and increases free radical stress cell resistance. The antiviral effect for specific viruses has been established as an antiviral effect for herpes simplex virus type 2 and bovine viral diarrhea virus (hepatitis c virus).